L-Methylfolate (also known as5-MTHF) is the active form of folate (vitamin B9) that the body can use directly. Unlike folic acid, it doesn’t require conversion by the liver, making it more effective.

Yes, it’s often recommended for pregnant women (especially those with MTHFR mutations) to support fetal development. However, always consult a doctor before use.

People with MTHFR mutations, low folate, depression, or those on medications that deplete folate (like methotrexate). Pregnant women may also benefit under medical guidance.

Most people tolerate it well, but some may experience mild nausea, digestive upset, or sleep issues. Reduce the dose or take it earlier if needed.